S/MARt DB - S/MAR

AC  SM0000109
XX
DT  1.1.1999 00:00:00 (created); ili
DT  30.7.2001 18:39:00 (updated); ili
XX
NA  HS$apoB-5MAR1
XX
OS  human, Homo sapiens
OC  eukaryota; animalia; metazoa; chordata; vertebrata;
OC  tetrapoda; mammalia; eutheria; primates
XX
SZ  ca. 964 bp
XX
LO  2
DE  G000205; apolipoprotein B
DP  Direction: 5'; 2765 - 1801
DN  Internal: n; Gene position numeral: 1
DC  positions refer to an Pst I-Hind III fragment [1];
DC  numbering system from Ludwig et al., DNA 6: 363-372 (1987)
DC  was used [1]

G000205;
apolipoprotein B

XX
SF  contains AATAAATAAA motif [1]
XX
FF  proximal S/MAR [1]; caution: in a reinvestigation either
FF  this or the more distal S/MAR failed to bind in standard
FF  assays [2]
XX
CP  HepG2 [1]
CN  CaCo-2 & HeLa [1]
XX
EV  in vitro selection of S/MAR [1]
EV  in vivo selection of S/MAR [1]
XX
RN  [1]
RX  MEDLINE; 90078221 PubMed; 2592370
RA  Levy-Wilson, B., Fortier, C.
RT  The limits of the DNase I-sensitive domain of the human
RT  apolipoprotein B gene coincide with the locations of
RT  chromosomal anchorage loops and define the 5' and 3'
RT  boundaries of the gene
RL  J. Biol. Chem. 264:21196-21204 (1989)
RN  [2]
RX  MEDLINE; 98187656 PubMed; 9528807
RA  Namciu, S. J., Blochinger, K. B., Fournier, R. E. K.
RT  Human matrix attachment regions insulate transgene
RT  expression from chromosomal position effects in Drosophila
RT  melanogsaster
RL  Mol. Cell. Biol. 18:2382-2391 (1998)
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