S/MARt DB - S/MAR

AC  SM0000505
XX
DT  24.2.2004 13:19:00 (created); ili2
DT  24.2.2004 14:59:00 (updated); ili2
XX
NA  HS$TH-MAR3
XX
OS  human, Homo sapiens
OC  eukaryota; animalia; metazoa; chordata; vertebrata;
OC  tetrapoda; mammalia; eutheria; primates
XX
SZ  1610 bp
XX
LO  11p15
DE  G002008; tyrosine hydroxylase
DC  contains the transcription start site [1]
XX
SQ  CTGCAGGGCCCGGGGGTGTGGGCAGATGGCACTCCTAGGAACCACGTCTACGAGACACAC
SQ  GGCCTGGAATCTTCTGGAGAAGCAAACAAATTGCCTCCTGACATCTGAGGCTGGAGGCTG
SQ  GATTCCCGTCTTTGGGGCTTTCTGGGTCGGTCTGCCACGAGGTTCTGGTGTTCATTAAAA
SQ  GTGTGCCCCTGGGCTGCCAGAAAGGCCCCTCCCTGTGTGCTCTCTTGAGGGCTGTGGGGC
SQ  CAAGGGGAACCTGGCTGTCTCAGCCCCCCGCAGAGCACGAACCCCTGGTCCCCGCAAGCC
SQ  CGCGGGCTGAGGATGATTCAGACAGGGCTGGGGAGTGAAGGCAATTAGATTCCACGGACG
SQ  AGCCCTTTCTCCTGCGCCTCCCTCCTTCCTCACCCACCCCCGCCTCCATCAGGCACAGCA
SQ  GGCAGGGGTGGGGGATGTAAGGAGGGGAAGGTGGGGGACCCAGAGGGGGCTTTGACGTCA
SQ  GCTCAGCTTATAAGAGGCTGCTGGGCCAGGGCTGTGGAGACGGAGCCCGGACCTCCACAC
SQ  TGAGCCATGCCCACCCCCGACGCCACCACGCCACAGGCCAAGGGCTTCCGCAGGGCCGTG
SQ  TCTGAGCTGGACGCCAAGCAGGCAGAGGCCATCATGGTAAGAGGGCAGGTAGGTGCCCGG
SQ  CGGCCGCAGTGGACCGGAGCCCAGGGCTGGTGCCAGCTGCCTCTGCTACTCCCCAGCCCT
SQ  GGCTGGCAGCCCCAGGCTCAGGGTCCATGCAAACCCCTGGGACGCCAGCGTGGATGTGGA
SQ  GGCCTGGGCACAGCGGCATCCCCTGTGCCTGGTGTTTGAGTCCCTGTTGGGGGAGGGTGA
SQ  GGTGATGCCTGTCCCTGTGTGTGCCCCTCTTAGGCCGACCTCTCTCGGGGGTCGTGTGGG
SQ  TCTCTGTGTCTTGTTTCATCTTGAATCTTAACGATCGGAATGTGGAAACAAATCCATCCG
SQ  AAAAAATCCAAGATGGCCAGAGGTCCCCGGCTGCTGCACCCAGCCCCCACCCTACTCCCA
SQ  CCTGCCCCTGCCTCCCTCTGCCCCAGCTGCCCTAGTCAGCACCCCAACCAGCCTGCCTGC
SQ  TTGGGGAGGCAGCCCCAAGGCCCTTCCCAGGCTCTAGCAGCAGCTCATGGTGGGGGGTCC
SQ  TGGGCAAATAGGGGGCAAAATTCAAAGGGTATCTGGGCTCTGGGGTGATTCCCATTGGCC
SQ  TGTTCCTCCCTTATTTCCCTCATTCATTCATTCATTCATTCATTCACCATGGAGTCTGTG
SQ  TTCCCTGTGACCTGCACTCGGAAGCCCTGTGTACAGGGGACTGTGTGGGCCAGGCTGGAT
SQ  GATCGGGAGCTTTTCAGCCCACAGGAGGGGGTCTTCGGTGCCTCCTTGGGCACTCAGAAC
SQ  CTTGGGCTCCCTGGCACCTTTAAAATGGGTTTTTATTTATGGACCTTGATTGAAATGTGG
SQ  TGTGAGTTGTAGCAGTGTCATTCCAGGTACCTTCTCAGGGACACAGGGCGCCCTCCCCCG
SQ  TCCTCCCCCGCCCTCCCCTACCCTCCCCCACCAGGCTCCCCATCAGGCATCCCCTCCCCA
SQ  GGGCGCCCCGGGGCCCAGCCTCACAGGCTCTCCGTGGCCTGGAACTGCAG
SC  EMBL #M23597; nt 1-1609, edited
XX
FT  547 - 648: exon 1.2 sequence [1]
FT  1562 - 1610: exon 2 sequence [1]
XX
SF  one of five successive fragments with MAR properties
SF  [1]; contains microsatellite repeat which acts as a
SF  silencer [1]
XX
BP  fragment with the lowest affinity to the nuclear matrix [1]
TP  tissue-specific [1]
XX
FF  attachment is considered to be dependent on tyrosine
FF  hydroxylase gene activation [1]
XX
CP  adrenal medulla [1]
CN  liver [1]
XX
EV  re-binding assay (LIS) [1]
EC  matrices from normal bovine tissues [1]
XX
DR  EMBL: M23597; HUMTHC
XX
RN  [1]
RX  MEDLINE; 22218497 PubMed; 12231434
RA  Lenartowski, R., Goc, A.
RT  Tissue-specific association of the human tyrosine
RT  hydroxylase gene with the nuclear matrix
RL  Neurosci. Lett. 330:151-154 (2002)
//