S/MARt DB - S/MAR

AC  SM0000514
XX
DT  27.2.2004 18:07:00 (created); ili2
DT  1.3.2004 13:39:00 (updated); ili2
XX
NA  MOUSE$SBS-T4
XX
OS  mouse, Mus musculus
OC  eukaryota; animalia; metazoa; chordata; vertebrata;
OC  tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae;
OC  murinae
XX
SZ  ca. 500 bp
XX
LO  9
DE  G009262; 
DP  Direction: 3'; Pos 1: transcriptional start
DN  Internal: n; Gene position numeral: -1
DE  G009263; 
DP  Direction: 3'; Pos 1: transcriptional start
DN  Internal: n; Gene position numeral: -2
DE  G009264; 
DP  Direction: 3'; 7300 - ; Pos 1: transcriptional start
DN  Internal: n; Gene position numeral: -3
DE  G009265; EPM2A (laforin) interacting protein 1
DP  Direction: 3'; Pos 1: transcriptional start
DN  Internal: n; Gene position numeral: -4
DE  G009266; 
DP  Direction: 5'; Pos 1: transcriptional start
DN  Internal: n; Gene position numeral: -5
DE  G009267; 
DP  Direction: 5'; Pos 1: transcriptional start
DN  Internal: n; Gene position numeral: 1

G009266;
G009265;
EPM2A (laforin) interacting protein 1
G009264;
G009263;
G009262;
G009267;

XX
SF  A/T/C sequence context [1]; stated to show some
SF  homology to intron 1 of p53 [1]
XX
FF  obtained in a search for SATB1 binding sites in vivo
FF  [1]; genes AA274079, BC025574 and AU051681 are
FF  downregulated to different extent in the thymus of SATB1
FF  knockouts while Mlh1, Epm2aip1 and AW209596 are not
FF  affected [1]
XX
CP  thymus [1]
XX
EV  flourescence in situ hybridization (FISH) [1]
EC  amplified FISH was shown for halos from wt and SATB1
EC  knockout cells [1]
XX
BF  SB000001; SATB1 [1]
MM  assessment of the dissociation constant; 4-8 nM
SO  mouse; mouse
QA  6
BF  SB000001; SATB1 [1]
MM  chromatin immunoprecipitation (ChIP); 
SO  mouse thymus; mouse
QA  6
XX
RN  [1]
RX  MEDLINE; 22608347 PubMed; 12692553
RA  Cai, S., Han, H.-J., Kohwi-Shigematsu, T.
RT  Tissue-specific nuclear architecture and gene expression
RT  regulated by SATB1
RL  Nat. Genet. 34:42-51 (2003)
//